Lentz's
Laboratory
Our laboratory focuses on the relation between simple lipid membrane structure
and dynamics and the functions of complex cellmembranes in the life and
activities of cells. At present, we have two major projects:
the role of platelet membranes in
regulating thrombin formation during
blood coagulation, and the molecular mechanism of membrane
fusion. Our focus is
primarily on these physiological processes, and we use those methods
that we need to answer our questions. However, it is fair to say
that we have special expertise in steady-state and frequency-resolved fluorescence
spectroscopy, differential scanning calorimetry, thermodynamics of protein-lipid
interactions, kinetic mechanisms of surface mediated enzymatic reactions,
computer simulation of complex processes based on simple thermodynamic
or kinetic models.
Recent Publications
'A
Crazy Idea',Endeavors
'A
Question of Clotting',The
Scientist
Folks in the Lab
Back row: (left to right) Lisa Phillippie, Rinku
Majumder,
Front row: (left to right) Gabriel Weinreb, Moses D. Sekaran,
Barry
Lentz,
Md. Emdadul Haque
Mailing address: 418
MEJB CB#7260, UNC, Chapel Hill, NC 27599
Lab phone: 919-962-8317;
Barry's
phone: 919-966-5384
Fax: 919-966-2852